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Mar 17, 2025
In today's web3 landscape, the convergence of AI and blockchain is driving the next wave of innovation.
At 0G, we've long been committed to building an ecosystem where visionary projects can thrive, leveraging our AI-native Layer 1 infrastructure to push the boundaries of what's possible.
With this vision in mind, we launched Guild on 0G—a series dedicated to showcasing the builders pioneering decentralized AI innovation. In this first edition, we’re spotlighting three standout projects: zer0, H1uman, and Avinasi Labs, each harnessing AI and blockchain to reshape the future of web3.
Join us as we explore how these initiatives are harnessing 0G's capabilities to drive transformative change onchain.
zer0: AI-Powered Liquidity for DeFi

Over the past decade, decentralized exchanges have reshaped crypto trading, but challenges like inefficient liquidity, limited accessibility, and cost constraints persist. zer0, a next-generation DEX, is tackling these issues with advanced automation and smart liquidity management, making DeFi faster, more accessible, and more efficient.
Core Features
AI Automated Liquidity Management (AIALM): Uses AI predictions to dynamically manage liquidity pools, reducing slippage and maximizing capital efficiency.
Voice/Text-Based DeFi Agent: Allows users to execute swaps, add liquidity, or set conditional orders using natural language commands via Telegram or web-based widget.
DefAI Tech Stack: zer0 hosts AI models directly onchain, making liquidity strategies transparent, community-driven, and highly efficient.
Why 0G?
AI Liquidity Management: zer0’s AI models for price prediction and liquidity optimization are stored on 0G’s DA Layer, ensuring low-cost, onchain AI computation.
Execution & Settlement: 0G’s consensus layer ensures sub-second finality, enabling AI-driven liquidity adjustments and seamless DeFi agent execution, minimizing front-running risks.
Scalability & Efficiency: zer0 runs on 0G’s execution layer, enabling onchain price predictions and low-cost liquidity management while reducing gas fees by 99%+ compared to Ethereum
By integrating AI into DeFi, zer0 is positioned to be a major contributor to liquidity within the 0G ecosystem, helping to set a new standard for decentralized trading and automated financial strategies.
H1uman: Decentralized AI Agent Factory

Developing artificial intelligence has traditionally required deep technical expertise and specialized resources, creating barriers for innovators. Humans.ai’s H1uman (H1) seeks to circumvent these obstacles with a user-friendly, decentralized platform that makes building and deploying AI agents more accessible than ever.
Core Features
AI Agent Factory: The H1 platform lowers the barriers to AI agent creation, allowing users to easily build and deploy agents through an intuitive, user-friendly environment with no deep technical expertise required.
Incentive Mechanism: Users who register AI Agents are labeled “developers,” while registered AI Agents are called “AI Miners.” AI Miners generate passive income for developers through an integrated DeFi rewards mechanism.
Diverse Use Cases: From AI-powered meme tokens to AI-driven DeFi tools, H1 opens up accessibility to AI to a wider web3 audience.
Why 0G?
AI-Native Infrastructure: H1’s AI Agent Factory V1 launch on 0G leverages 0G’s AI-native infrastructure, including on-prem GPUs for AI model execution and HDD storage, ensuring efficient and scalable AI operations.
NFT-Based Trust Layer: H1 utilizes 0G’s unique trust layer, allowing transparent verification of AI models and fostering a decentralized, community-driven AI ecosystem.
Decentralized AI Innovation: 0G’s infrastructure supports AI-powered token creation, advanced AI DeFi tools, and collaborative AI model evolution, making it the ideal home for H1’s vision of community-powered AI development.
By lowering the barrier to AI innovation, H1uman is driving deeper onchain engagement and expanding AI’s role within web3 applications.
Avinasi Labs: AI for Longevity Research

Scientific progress in longevity research has long been hindered by data accessibility challenges. Avinasi Labs is seeking to revolutionize the field by creating the first AI-native graphic layer for longevity, allowing users to contribute health data in a secure, incentivized, and decentralized way.
Core Features
Reward-Based Framework: Avinasi incentivizes users to contribute encrypted biodata to earn rewards, creating a verifiable dataset that fuels scientific research on aging.
Collaborative Research: Avinasi Labs’ participant methodology expands a substantial dataset on aging and longevity research to be used by researchers globally.
AI Insights: As Avinasi’s resources grow, scientists will be able to train models on securely encrypted longevity datasets, leveraging advanced analytics to uncover patterns in aging and longevity.
Why 0G?
Secure Biodata Storage: Avinasi stores encrypted, append-only biodata on 0G’s log layer, ensuring data integrity and accessibility. This biodata can be downloaded by anyone, but can only be decrypted by the TEE running a specific program.
Durable Data Storage: 0G’s erasure-coding mechanism and PoRA guarantee data durability, preventing loss and ensuring long-term reliability.
High-Throughput AI Processing: 0G’s scalable infrastructure supports large-scale data processing, making it ideal for storing biodatasets and enabling scientists to train models on encrypted data.
By democratizing longevity research, Avinasi Labs is creating a global, user-driven dataset, enabling individuals to actively shape the future of health and aging science.
Guild on 0G
Guild on 0G is all about celebrating the projects that are pushing the limits of blockchain and AI. From zer0’s AI DeFi automation to H1uman’s democratized agent creation and Avinasi Labs’ decentralized longevity research framework, these projects are shaping the future of web3 in ways that only AI can power.
As the 0G ecosystem grows, we will continue to highlight the builders and visionaries at the forefront of decentralized AI. Stay tuned for the next edition of Guild on 0G, and in the meantime, be sure to take a deeper dive into zer0, H1uman, and Avinasi Labs.
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